Healthy Brains Financing Initiative

Mental and neurological illnesses are the world’s biggest unmet medical need: affecting 1 in 4 people and resulting in $3 trillion in annual global costs. Despite this, most countries contribute limited resources to brain health research, creating a dire need for innovative investment approaches.

Global Mental Health Program

About Healthy Brains Financing Initiative

The Healthy Brains Financing Initiative (HBFI) is a collaboration of global leaders in neuroscience, policy, and finance to develop an umbrella set of financing mechanisms to fuel an unprecedented increase in brain science breakthroughs, from basic research to implementation, that will change the lives of those living with mental and neurological disorders and bend the unsustainable $3 trillion global cost curve borne today by low, middle, and high income countries. Planning efforts for this initiative are currently underway with a formal launch planned for 2021.

National Academy of Medicine One Mind

Funding the Most Needed Science:

HBFI will make research investments based on the need for this funding relative to the scale of unmet public health need, the potential for improving lives, the scientific opportunity presented by that research. HBFI will support many types of research on multiple topics throughout the duration of the initiative.

Initial Research Focus: Brain Development and Disorders in Young Adults

Most mental health problems emerge between the ages of 11 and 30 and lifetime health habits are also formed during this time.  Despite this, there has been less investment in research for people of these ages than for their younger or older counterparts. HBFI will fund research to explore this important period of biological and social change to improve understanding of how to treat and prevent mental and neurological conditions.

Funding Youth Mental Health photos

Guiding Principles

Include diverse populations in low-, middle-, and high-income countries

Involve those with lived experiences

Need for rigor, replicability, and generalizability

Strongly support data sharing and open science

Learn from the last half century of translational failure: no business as usual

A Collaboration of Global Experts


Garen Staglin - About One Mind


One Mind

Victor Dzau - Healthy Brains Financing Initiative


National Academy of Medicine

HBFI has four working groups to develop key strategies and implementation plans prior to the 2021 launch. These individuals are global leaders in their respective fields and are graciously donating their time to make HBFI a success.


HBFI Financing Structure


CHAIRS: David Chen, Equilibrium Capital; Valerie Conn, Science Philanthropy Alliance; Robert Klein, Klein Financial Corporation


  • Margaret Anadu, Goldman Sachs
  • Daniel Arbess, Xerion Investments
  • Karim Barrada, HSBC
  • Mukesh Chawla, World Bank Group
  • Norm Friedland, Fulsky Partners
  • Anshul Krishnan, Social Finance
  • Chris Lee, Milken Institute
  • Pierre Meulien, Innovative Medicines Initiative
  • Chris McCahan, IFC
  • Tracy Palandjian, Social Finance
  • Russell Schofield-Bezer, HSBC
  • Mel Spigelman, TB Alliance, Word Bank
HBFI Use of Proceeds


CHAIRS: Steve Hyman, Broad Institute of MIT and Harvard; Miranda Wolpert, Wellcome Trust


  • Cara Altimus, Milken Institute
  • Robin Buckle, UK Medical Research Council
  • William Carson, Otsuka Pharmaceutical Development & Commercialization
  • Alon Chen, Weitzmann Institute
  • Valerie Conn, Science Philanthropy Alliance
  • Murali Doraiswamy, Duke University
  • Harris Eyre, CNSDose
  • Howard Fillit, Alzheimer’s Dementia Discovery Fund
  • Mona Hicks, One Mind
  • Richard Huganir, Johns Hopkins University
  • Tom Insel, Mindstrong Health
  • Danielle Kemmer, Graham Boeckh Foundation
  • Devora Kestel, World Health Organization
  • Walter Koroshetz, National Institute for Neurological Disorders and Stroke
  • Husseini Manji, Janssen
  • Beverly Pringle, National Institute of Mental Health
  • Shekhar Saxena, T.H. Chan School of Public Health, Harvard University
  • Paul Stoffels, Johnson & Johnson
  • Melissa Turgeon, Massachusetts General Hospital
  • Andrew Welchman, Wellcome Trust
HBFI Pay for Metrics


CHAIRS: Chris Murray, University of Washington; Eliot Sorel, George Washington University


  • Yueqin Huang, Institute of Mental Health/ The Sixth Hospital, Peking University, Bejing
  • Mark McClellan, Duke University
  • Gerald McDougall, PwC
  • Mark Mynhier, PwC
  • Jennifer Payne, Johns Hopkins University
HBFI Governance


CHAIRS: Tim Evans, McGill University; Brad Herbert, Brad Herbert Associates


  • Sung Hee Choe, FasterCures, Milken Institute
  • Mickey Chopra, World Bank Group
  • Miyoung Chun, Alzheimer’s X / MIT Sloan School of Management
  • Mark Feinberg, International AIDS Vaccine Initiative
  • Tom Kalil, Schmidt Futures
  • Patrick Kennedy, The Kennedy Forum
  • Craig Kramer, Johnson & Johnson
  • Muhammad Pate, World Bank Group
  • Vikram Patel, T.H. Chan School of Public Health, Harvard University
  • Shekhar Saxena, T.H. Chan School of Public Health, Harvard University
  • Mointreyee Sinha, citiesRISE
  • Eliot Sorel, George Washington University
  • Nora Super, Governance
  • Graham Thornicroft, Institute of Psychiatry, King’s College London

Why One Mind's Support Matters

One Mind and the National Academy of Medicine are leading HBFI in collaboration with the World Bank and the World Health Organization, as well as leading investment banks, grant-making organizations, and research organizations. One Mind plays a key role in bringing all of these groups together and in making sure that those who have lived experience with brain health disorders are represented in this initiative.