One Mind is accelerating brain health for all.

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It's No Joke Comedy Promotion

IT'S NO JOKE - A Comedy Benefit for Mental Health

We are pleased to announce our newest event, ‘It’s No Joke,’ a comedy benefit for mental health headlined by Howie Mandel and featuring Maria Bamford and Yamaneika Saunders. The event will take place on September 23 at the Uptown Theatre in Napa, California. Join us for an unforgettable night of laughs while celebrating brain health research.
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The One Mind Mission

One Mind accelerates collaborative research and advocacy to enable all individuals facing brain health challenges to build healthy, productive lives.


Accelerate research to generate breakthroughs that translate into scalable diagnostic methods and cures


Amplify the voices of those with lived experience, guiding programs to meet the community’s needs


Educate society to foster the global acceptance and empowerment of neurodiversity
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One Mind Global Impact

Inspired by the founders’ lived experience, One Mind is the leading brain health nonprofit committed to healing the lives of people impacted by brain illness and injury through global, collaborative action.

$513 M

Raised and leveraged to support life-saving brain health research

26 M

People receiving improved mental health support via the One Mind at Work Charter


People enrolled in and benefitting from One Mind funded studies
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I am living proof that with loving family support, continued involvement in one’s community, and science-based early medical care, one can recover from even the most scary, depressing, debilitating of psychiatric illnesses.

Brandon Staglin

One Mind President and Schizophrenia Survivor