There is more to mood disorders, such as bipolar disorder and major depression, than meets the clinician’s eye. Fortunately, scientists such as Jun Li, Ph.D. are probing the genetic underpinnings of such diseases in pursuit of knowledge on which to build better therapies. Dr. Li, an Assistant Professor of Human Genetics at University of Michigan and a Rising Star Awardee in 2011, has just discovered 3 new candidate genes for bipolar disorder, and found a gene expression pattern underlying the disrupted sleep cycles of persons with mood disorders.

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