One Mind Rising Star Awards

• The project period for the awards is 3 years.
• The total funding for each Rising Star Research Award is $300,000, of which $100,000 will be distributed annually. Continuation of the awards for the second and third years of the research are dependent upon review of an annual progress report by the Chair of the One Mind Scientific Advisory Board and the One Mind Chief Scientist and Innovation Director.
• Indirect costs are limited to a maximum of 10% and will be taken from the direct costs.
• To qualify as an early career investigator, candidates should be within 10 years of their initial independent appointment as an assistant professor for academic institutions or equivalent for non-academic positions. Note that postdoctoral fellows are ineligible.
• Candidates should have demonstrated productivity and innovation in a scientific field that can be applied to the study of neuropsychiatric disorders, such as anxiety, addiction, bipolar disorder, depression, posttraumatic stress, schizophrenia, traumatic brain injury, suicidality, and other serious psychiatric illnesses.
• Awardees will be invited to attend One Mind’s Annual Music Festival for Brain Health activities on September 9-10, 2022 in Napa Valley and give a presentation about their award-winning research plans at the Music Festival’s Scientific Symposium.
• The proposal should not overlap with existing funding.

One Mind Rising Star Research Awards:

• The 2022 One Mind COMPASS Pathways Rising Star Awards will support grant proposals spanning basic/preclinical, translational, and clinical research for psychiatric disorders.
• These include, but are not limited to, schizophrenia, bipolar disorder, depression, obsessive-compulsive disorder, eating disorders, post-traumatic stress disorder, anxiety disorders, and suicidality. Studies at the intersection of addiction/substance use disorders and psychiatric disorders are within scope.
• Autism spectrum disorder, attention deficit/hyperactivity disorder, and neurodegenerative disorders are out of scope.

Examples of relevant research proposals include, but are not limited to, studies that aim to:

• Discover the molecular/genetic, synaptic, cellular, or circuit/network basis of psychiatric disorders in model organisms or humans.
• Advance biomarker development to improve diagnosis and/or treatment outcomes.
• Investigate common mechanisms of brain dysfunction between two or more disorders.
• Develop new experimental or computational approaches/model/tools for a sophisticated understanding of disease etiology, pathophysiology, resilience, and/or recovery.
• Evaluate therapeutic mechanisms and modes of action for interventions including pharmaceuticals, neurostimulation, digital therapies, and other cognitive/behavioral health interventions.
• Identify and/or test novel pharmacological and non-pharmacological therapeutic targets.
• Improve our understanding of how age, race/ethnicity, and/or comorbidities impact the diagnosis, prognosis, and treatment effectiveness.

Transdiagnostic investigations and research that bring us closer to precision psychiatry will be given special attention. Illustrative examples include metabolomics biomarkers, gut microbiome-brain interactions, psychedelics, closed-loop neurostimulation, natural language processing (NLP)-based biomarkers, and predictive analytics-based models for evaluating risk or treatment efficacy.

Each 2022 One Mind COMPASS Pathways Rising Star Award winner will receive::

• A research grant of $300,000 sponsored by COMPASS Pathways over a three-year project period.
• Eligibility for the One Mind Rising Star Development Program, enabling participation in select leadership development, entrepreneurship, media, and networking opportunities/events offered by One Mind.

• Applicants must be independent investigators (faculty or equivalent) already employed at the rank of assistant or associate professor (or equivalent) in a non-profit (public or private) academic or non-academic research institution.
• Applicants should be within 10 years of their initial independent appointment to qualify as an ECI.
• Applicants will have a doctoral level degree (e.g., MD, PhD, PsyD, PharmD, etc.) with demonstrated academic excellence and research productivity in scientific fields that can be applied to the study of psychiatric disorders.
• One Mind encourages applications from underrepresented minorities and women. There are no citizenship or geographical restrictions. International applicants are welcome to apply.
• Pre-doctoral students, postdoctoral fellows, and professors are not eligible to apply.
• Applicants can apply for the award only one time per year for a maximum of three times in their career.
• One Mind reserves the sole right to decide if an applicant meets the eligibility requirements.

April 21, 2022 Application portal opens

June 6, 2022 Applications due by 5 P.M. Pacific Time (PT)

July 16, 2022 Notification of decision (subject to change)

January 1, 2023 Earliest start date for the Award (subject change)