One Mind Rising Star Awards

 

About

One Mind launched the Rising Star Awards in 2005 under the fundamental principle that cutting edge, high-risk research would allow us to find the breakthroughs to accelerate cures for the neuropsychiatric illnesses that affect 1 in 4 people worldwide. Knowing that 90% of these conditions are treatable, we wanted to create a highly impactful grant that enables the researcher to think outside of the box and pursue research that might not otherwise be federally funded. Each One Mind Rising Star Award winner receives $300,000 over a three-year period to fund research for their studies, catalyzing innovation and encouraging collaboration and data sharing.

Since 2005, One Mind has awarded 36 awards to some of the best and brightest early career brain scientists. Since receiving their awards, these researchers have gone on to make a significant impact, both in their studies and in the brain health community as a whole. One such awardee is 2010 Rising Star Award winner, Dr. Joshua Gordon, who now serves as the Director of the National Institute of Mental Health.

2021 Application Window Will Likely Open in the Middle of April

2020 Award Application Information

One Mind, in collaboration with Janssen Research & Development and the Baszucki Brain Research Fund, offered 2 Rising Star Awards in 2020. In collaboration with Inscopix, we also offered two supplemental technology grants in support of the Rising Star Awards.

We are also pleased to announce that we were able to award 5 Bipolar Research Awards thanks to additional support from the Baszucki Brain Research Fund.

The application window for the 2020 Rising Star Awards closed on May 31, 2020. To learn about this annual grant opportunity, please read the information below. Additional information is also available on our Rising Star Awards FAQ page.

General Award Characteristics and Eligibility
  • The project period for the awards is 3 years.
  • The total funding for each Rising Star Research Award is $300,000, of which $100,000 will be distributed annually. Continuation of the awards for the second and third years of the research are dependent upon review of an annual progress report by the Chair of the One Mind Scientific Advisory Board and the One Mind Director of Science and Technology.
  • Indirect costs are limited to a maximum of 10% and will be taken from the direct costs.
  • To qualify as an early career investigator, candidates should be within 10 years of their initial independent appointment as an assistant professor for academic institutions or equivalent positions for industry or other non-academic positions. Note that postdoctoral fellows are ineligible.
  • Candidates should have demonstrated productivity and innovation in a scientific field that can be applied to the study of neuropsychiatric disorders, such as anxiety, addiction, bipolar disorder, depression, posttraumatic stress, schizophrenia, traumatic brain injury, suicidality, and other serious psychiatric illnesses.
  • Awardees will be invited to attend One Mind’s Annual Music Festival for Brain Health activities and give a presentation about their award-winning research plans at the Music Festival’s Scientific Symposium.
  • The proposal should not overlap with existing funding.
  • Applicants may apply for the One Mind/Inscopix Technology Grant only as a supplement to a Rising Star Award proposal. Applicants cannot solely apply to the Technology Grant.
Scope

One Mind Rising Star Research Awards:

Proposals for studies on any of a wide range of neuropsychiatric conditions are in scope (see face sheet on the application for examples), with studies focusing on bipolar disorder of special interest, including applications that would advance therapeutics for bipolar disorder, ranging from biomarkers to promising therapeutic modalities including neurostimulation. Examples of relevant research on neuropsychiatric and/or neurotraumatic disorders include, but are not limited to studies that aim to:

  • Discover biological mechanisms and therapeutic targets;
  • Develop new or refine existing models and research tools;
  • Identify or validate biomarkers;
  • Evaluate the effectiveness of therapies, including pharmaceuticals, electroceuticals, digital therapies or cognitive and behavioral health interventions to prevent the onset or promote recovery of neuropsychiatric disorders using pre-clinical or computational models or with pilot clinical studies;
  • Characterize similarities and differences between two or more neuropsychiatric or neurotraumatic disorders to advance personalized medicine;
  • Improve our understanding of how comorbid conditions, such as cancer and diabetes, as well as other neurological and non-neurological disorders, interact with neuropsychiatric disorders and impact diagnosis, prognosis and treatments;
  • Promote or restore brain health by conducting bi-directional and/or iterative translational research using existing clinical data or new data from small pilot clinical studies, in combination with relevant pre-clinical or computational models; or
  • Advance digital health, telehealth or other innovative approaches to increasing access to mental health care.
One Mind Bipolar Research Awards

To advance knowledge and grow the community of researchers, up to 10 proposals on bipolar disorder will also be considered to a one-time award of $10,000. The funds can be applied toward travel to the One Mind Music Festival or to other scientific meetings, to pilot studies, or to any other costs relevant to advancing research on bipolar disorder. Awards will be given to highly meritorious, runner up applications to the Rising Star Awards that have direct relevance to bipolar disorder. No indirect costs are allowed.

One Mind / Inscopix Technology Supplement Grant

Applicants whose proposals can be enhanced by optical methods to investigate links between neural circuit/ensemble dynamics and disease phenotypes are within scope and encouraged to apply for this supplemental award from Inscopix. Proposals might include, but are not limited to:

  • Signal analysis in health vs. disease, and/or how circuit/ensemble signatures change and evolve during disease progression an in therapeutic intervention paradigms.
  • Studies that use established or new rodent models of neuropsychiatric disorders to extract key characteristics of the pathophysiology in a cell type-and/or circuit-specific manner.
  • Investigations into the causal role of disease circuit/ensemble dynamics identified with nVoke/nVista and potentially in conjunction with other methods such as pharmacology, chemogenetics, electrophysiology and cell ablation.

Each Technology Grant includes:

  • 1 state-of-the-art nVoke miniature microscope system from Inscopix for integrated in vivo Ca+2 imaging and optogenetics (simultaneous or sequential) in the brains of freely behaving mice. Applicants can request an nVista system in lieu of nVoke should their proposal require only Ca+2 imaging either in the mouse brain and/or in the rat neocortex and hippocampus.
  • Full scientific support including a dedicated Field Scientific Consultant for the duration of the project to provide on-site training and guidance to the awardees, from experimental design to data analysis. The award will also provide an opportunity to engage with Inscopix’s transdisciplinary team of neuroscientists, data scientists, and engineers.
  • Full technical support including iCare (no questions asked repair and replacement service, for the duration of the award).

For complete details and scope parameters for the Inscopix Technology Supplement Grant, please read the 2020 Rising Star Award RFP.

One Mind Rising Star Award Winners

We are proud to have funded many of the most promising neuropsychiatric researchers in the field, powering studies that are transforming the face of brain health.

Research Updates

Curious about the progress recent Rising Star awardees have made on their funded research projects? We don’t blame you.
See All Research Updates

All Over the Map

Explore where past One Mind Rising Star Award winners and their affiliated universities are located.
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Partners

The One Mind Rising Star Awards are the result of contributions from partners who are as determined to accelerate the future of brain health as we are.