Steve Paul, MD

Steven M. Paul, M.D., is a neuroscientist, psychiatrist and biopharmaceutical executive. He is the Founder and Chair of the Board at Seaport Therapeutics and Rapport Therapeutics and Co-Founder and board member at Syremis Therapeutics as well as a Venture Partner at Third Rock Ventures. He has over 40 years of experience as a physician-scientist specializing in neuroscience and molecular neuropharmacology as well as CNS drug discovery and development. Dr. Paul previously served as the President and CEO of Karuna Therapeutics (now Bristol Myers Squibb), a biotechnology company developing medicines for schizophrenia and Alzheimer’s disease. Dr. Paul is also a co-founder and former board member of Sage Therapeutics and Voyager Therapeutics. Dr. Paul was the Founding Director of the Appel Alzheimer’s Disease Research Institute at Weill Cornell Medical College, as well as professor of neuroscience, psychiatry and pharmacology. He is currently a professor of neurology and psychiatry at Washington University School of Medicine in St. Louis. Dr. Paul spent 17 years at Eli Lilly and Company, during which time he served in several key leadership roles, including Executive Vice President of Science and Technology and President of the Lilly Research Laboratories. As President of the Lilly Research Laboratories, he was responsible for the company’s overall R&D strategy, expanding its efforts in neuroscience, diabetes, oncology, inflammation and biotechnology. Prior to Lilly, Dr. Paul served as a Laboratory/Branch Chief and the Scientific Director of the National Institute of Mental Health. He has also served as Medical Director in the Commissioned Corps of the United States Public Health Service. Dr. Paul has authored or co-authored more than 600 papers and book chapters. He is an elected fellow of the American Association for the Advancement of Science and a member of the National Academy of Medicine. Dr. Paul is the chairman of the board of the Foundation for the National Institutes of Health and board member at Scripps Research. Dr. Paul received his bachelor’s degree in biology and psychology from Tulane University, and his M.S. and M.D. degrees from Tulane University School of Medicine.