Our Portfolio

Amae Health

Amae Health is an integrated whole-person care provider specializing in treating severe mental illness (SMI), focused on personalized and lifelong treatment to deliver lasting health outcomes.

AMPA Health

Ampa is a health tech startup that is commercializing a scalable brain stimulation technology to treat depression, anxiety, and addiction. Ampa’s groundbreaking One Day treatment delivers a 70% remission rate from depression and anxiety.

Attune Neurosciences

Attune Neurosciences has built a non-invasive therapeutic platform to deliver neuromodulation to the deep brain using low-intensity focused ultrasound to address a number of psychiatric, neurological and human performance applications.

Biomia

Biomia is pioneering drug discovery and biomanufacturing of human-validated nature-inspired molecules in one platform. By integrating patient-derived data and human-based evidence of efficacy, AI-guided drug design, and scalable biomanufacturing, Biomia is developing a pipeline of novel, safe, and efficacious therapies for unmet needs in patients suffering from CNS disorders.

Birches Health

Birches Health is the leading national clinical program for modern digital addictions, covered by insurance and state funding. Birches Health’s mission is to provide convenient, comprehensive care and resources for individuals facing challenges related to gambling, sex and pornography, video gaming, and internet and social media addiction.

Ceretype

Ceretype is an in-market, audit-cleared brain “biomarker engine” – a novel fMRI platform incorporating optimal image acquisition and advanced analytics that de-risks and accelerates the development of psychiatric and neurological therapies.

Cerula Care

Cerula Care is a virtual behavioral healthcare practice that partners with specialists and tailors behavioral health care for adults with serious illness. Cerula Care is using AI/ML modeling to fuel clinical and cost outcomes related to improvement in behavioral health and reduction in hospitalizations.

Cognigenics

Cognigenics is a biotechnology company developing RNA-based long-acting therapeutics for mood disorders, memory loss, and cognitive impairment—offering non-invasive, non-systemic, safe, scalable, and effective solutions that transform lives.

Deliberate Ai

Deliberate AI advances precision neuroscience and psychiatry by developing multimodal biomarkers and individualized phenotypes. Through Advanced Diagnostics & Monitoring, Precision Therapy Enablement, and Ambient Clinical Intelligence, we enhance both clinical trials and patient care, enabling timely and personalized treatment strategies.

Dionysus Health

Dionysus is developing the first clinically validated epigenetic tests to diagnose hormonal depressions like postpartum depression, PMS, and menopause in women, and to offer precision medical insights to enable the most effective treatments.

Ellipsis Health

Ellipsis Health has developed the first-ever voice-based biomarker powered co-pilot for behavioral health by layering on case management, primary care, and urgent care calls. With minutes of speech, Ellipsis Health can in real-time screen for anxiety and depression and triage to different pathways based on severity.

Eratos Therapeutics

Eratos Therapeutics is revolutionizing CNS drug discovery with its groundbreaking approach, integrating spatial computing and AI-driven nanoscale mapping to build ground-truth world models of the brain. By leveraging advanced technologies, Eratos identifies high-specificity therapeutic targets and expedites the development of precision-engineered therapeutics for neurodegenerative, neuroinflammatory, and neuropsychiatric disorders.

Fareon

Fareon (formerly known as Humanity Neurotech) is a clinical-stage medical device company developing a new class of transformative technologies for psychiatric and neurological brain disorders by targeting neuroinflammation and mitochondrial dysfunction.

Flock Health

Flock is a digital health company working to detect and reduce acute mental health crises for patients suffering from Serious Mental Illness and, in doing so, improve patient wellbeing and health outcomes while lowering spend on inpatient and emergency care.

Flourish Labs

A mental health company designed for Gen Z, growing the mental health workforce by training certified peer supporters and delivering 1-on-1 peer support for young adults and teenagers on a HIPAA-compliant telehealth platform.

Flow Neuroscience

Flow Neuroscience is pioneering a new category of at-home electric medicine and delivering drug-free, brain-based treatments for mental health. Flow is world’s first clinically validated FDA approved at-home transcranial direct current stimulation (tDCS) headset. Since its European launch in 2019, Flow has become the only CE-marked at-home tDCS treatment for depression used by the NHS, empowering more than 55,000 people to take control of their mental health. With FDA approval in 2025, the US joins the UAE, Australia, Brazil, the UK and EU as countries where Flow’s accessible depression treatment is available.

Flowly

Flowly is a clinically validated platform for managing stress and building resilience in teams. Using a mobile app and VR headset, Flowly collects biometric data such as heart rate and converts it to visualizations in virtual experiences that reduce feelings of stress and burnout by 20 – 100%.

Forecast Bio

Forecast Bio is building an AI-powered preclinical platform that directly links complex cellular neurobiology to patients’ mental health outcomes. By mapping how new drugs impact human brain circuits and symptoms, Forecast is speeding up therapeutics development by 10x—and radically transforming what’s possible in brain and mind health.

Fort Health

Fort Health is a pioneering provider of insurance-based mental health care for children and adolescents, dedicated to improving access and outcomes through collaborative care and evidence-based treatment. By combining innovative technology with expert clinical teams, Fort Health empowers families to navigate mental health challenges with ease and confidence.

Freedom Bioscience

Freedom Biosciences is a Yale spin-out and clinical stage biotech company developing next generation depression treatments based on ketamine and 5th-based tryptamines.

Function

Function Health is a personal health co-pilot that starts with understanding your body through all-in-one lab testing. Function’s membership includes 100+ advanced lab tests, with results delivered alongside easy-to-read, actionable insights developed with the world’s top doctors.

Heading Health

Heading Health is a mental healthcare provider offering a personalized and holistic approach to treatment, guided by cutting-edge research and technology.

Holobiome

Holobiome is a B2B platform company building the world’s most comprehensive collection of human gut bacteria, and using it as a tool to map how the gut microbiome influences our biology. First unraveling the gut-brain-axis, Holobiome seeks to translate these discoveries into better food, consumer products, and drugs to give humanity the tools it needs to combat major problems like depression and pain.

Humans Anonymous

Humans Anonymous is building anonymous audio spaces for mental health. Members join daily meetings to share their struggles, get advice, and support each other. Communities include loneliness, depression, anxiety, and more

Jimini Health

Jimini Health is leveraging AI and deep clinical innovation to develop radically more effective, engaging, and scalable mental health solutions, a critical and necessary innovation when anxiety, depression, and loneliness top the list of unmet medical needs.

Limbic

Limbic is a clinically-validated AI agent for mental healthcare, used by health systems and payers across the UK and US. The AI has supported more than 600,000 patients in treatment, and is the only AI mental health chatbot approved as a Class II medical device, supported by a growing evidence base of seven peer-reviewed studies, including in Nature Medicine.

Luna Joy

LunaJoy Health is a behavioral health integration company that works directly with medical doctors and payors to identify unmet service needs for women and deliver, in specialized networks, medication management, therapy and coaching.

manatee

Manatee is a family mental health provider addressing the pediatric mental health crisis by treating the entire family system, including parents. Their evidence-based, whole-family model is proven to be 4x more engaging and 3x more effective than traditional, child-only therapy.

Metabolic Psychiatry Labs

Metabolic Psychiatry Labs (MPL) treats serious mental illness with metabolic precision remotely through food, real-time data, and expert clinical care. With a Stanford-backed proprietary treatment protocol at its core, MPL provides customized treatments with proven outcomes and supports providers and patients in their treatment with evidence-based nutrition and metabolic therapeutic approaches.

Mindstate Design Labs

Mindstate Design Labs is a techbio platform and clinical-stage psychiatric therapeutics company using AI to precision-design psychoactive effects that drive targeted reintegrations of neural connectivity.

Monument Therapeutics

Monument Tx is a neuroscience-focused drug development company using digital biomarkers to develop more targeted treatments for psychiatric and neurological disorders. Lead program MT1988 is currently in a large patient study in clinical high risk for psychosis individuals to assess its potential to improve cognitive impairment associated with schizophrenia and validate its predictive digital biomarker.

Motif Neurotech

Motif Neurotech is a company creating minimally invasive bioelectronic implants that monitor and treat severe mental health conditions.

Neuroblox

Neuroblox is a computational neuroscience platform that simulates patient-specific brain and behavioral responses to clinical interventions and their targets. The platform empowers the development of new drugs and devices, and improves clinical trial success and treatment selection through precision neurotherapeutics.

Neurofundus

Neurofundus is collaborating with psychiatric hospitals in multiple countries to collect and generate multimodal data on thousands of patients with psychiatric disorders (starting with depression). These data will be used to build a foundation model - comprehensively mapping the phenotype and biology of depression patients - to enable personalized treatment trajectories and precision approaches to drug/biomarker discovery.

Nosis Health

Nosis is building a new model for substance use care – one focused on building health and vitality, not just stopping use. By combining addiction medicine, advanced diagnostics, therapy, coaching, and lifestyle interventions, we help people heal their brains, rebuild their bodies, and create the conditions for lasting wellbeing.

Options MD

Options MD is a telehealth company enabling patients to access mental health care and treatment options that address severe and treatment-resistant mental illnesses, starting with treatment-resistant depression (TRD).

Orbit

Orbit is building foundation models of cognitive states and conditions, enabling precision mental healthcare. They are collecting unprecedentedly rich neural data-sets, enabled by their novel brain wearable which can achieve fMRI-comparable resolution at scale.

Pangea Bio

Pangea Bio is a biotechnology company developing transformative medicines for psychiatric and neurological disorders, by deploying AI to uncover promising molecules inspired by nature’s diverse chemical space.

Radicle Science

Radicle Science is a healthtech public benefit corporation on a mission to transform the $1T global wellness industry by enabling rigorous science at unprecedented speed, scale, and precision. By fusing AI, consumer science, and massively scalable real world clinical trials, Radicle is enabling a new generation of proven, precision nonprescription treatments–accessible to all.

Sanarai

Sanarai is a mental health platform for Spanish-speakers, addressing the gap in mental health offering for the Latinx community.

Sanmai

Sanmai is a neurotechnology company developing non-invasive ultrasound neurotherapeutics for mental health and neurological disorders, combining transcranial ultrasound stimulation with AI-driven software to deliver safe and effective treatments.

Slingshot

Slingshot is the AI research lab behind Ash (www.talktoash.com), the first AI designed for therapy. By building the first foundation model for psychology Slingshot aims to make mental healthcare more accessible. The company has built dozens of domain-specific AI models for clinical mental health and tested them in a private beta with 20K+ people.

SocialRx

SocialRx (formerly known as Art Pharmacy) is a leading social prescribing platform that helps health plans, employers, and universities tackle the growing crisis of loneliness and mental health through arts, culture, and nature. By combining technology, human-centered care navigation, and evidence-based models, SocialRx transforms community connection into measurable improvements in mental well-being and belonging across the United States.

Somethings

Somethings is a platform connecting teenagers with certified Peer Mentors who are trained to provide mental health support through a novel, digital first care delivery method.

Soulside

Soulside is an AI-powered mental health platform that enables clinical professionals to deliver effective group support for high-risk adults. We first focus on enabling nurse-led groups for pregnancy and postpartum support.

Tetricus Labs

Tetricus Labs is a precision psychiatry company leveraging breakthrough AI computational neuroscience to deliver the right diagnosis and treatment recommendation for every patient.

Townhome Health

TownHome Health is a non-traumatic alternative to hospitalization for urgent mental health crises; after staying at calm “Crisis Respite” homes for two weeks, guests reduce their future hospitalizations by 75% with the 24/7 support of our tech-enabled peer clinicians.

Vita Health

Vita Health delivers virtual therapy proven to reduce the likelihood of death by suicide by 60-80%. Vita Health is the only clinically proven, evidence-based solution focused on suicide risk reduction and prevention.

Vitalic

Vitalic is a geriatric-specialized and team-based behavioral health practice that uniquely provides the proactive outreach and engagement required to enroll and treat the often reluctant 65+members into behavioral health care that is proven to improve clinical outcomes while reducing total cost of care.

Xylo Bio

Xylo Bio is developing targeted neurotherapeutics designed to rewire neural circuits and restore brain function. Combining advanced neuroscience with computational drug discovery, Xylo Bio is developing optimized treatments to revolutionize care for neurological and psychiatric conditions.

Zama Health

ZAMA is a sports psychology and mental wellbeing platform for athletes and the broader fitness community. Specifically, the platform provides access to digital modules, a peer community, motivational support, and a clinical network that optimizes both the mental and physical health of its users. ZAMA is a B2B SaaS platform that contracts directly with athletic departments, fitness companies, and gyms.

Work with Our Companies

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