Developing a Brighter Future for At-Risk Youth

Serious Psychiatric Illness (SPI) is a major public health issue, devastating individuals, families and society. Starting between ages 16 and 30, the one in 25 people who live with SPI face hallucinations and delusions (psychosis), lack of motivation, inability to think clearly, tremendous social stigma, and high rates of substance abuse and homelessness, leading often to suicide. Schizophrenia alone costs the U.S. $156 billion annually. Currently only 8% of youth with early SPI receive gold-standard early care, and only 22% of patients fully recover from SPI.

One Mind believes in a brighter future.

Through One Mind’s ASPIRe (Applications for Serious Psychiatric Illness Recovery) initiative, we aim to enable 75% of youth with early SPI to receive gold-standard care and the proportion of patients who recover from SPI to rise to 75% by 2040.

How will we start to address these issues?

In the near term, our immediate interest consists of two deliverables:

  • To start a learning healthcare network in California for early SPI community-based programs to share data and ideas so that each can learn from one another’s strengths, improving patient care on a large scale.
  • To pilot research-based care innovations and support innovative ways to enroll young people with early SPI.

Results from the NIMH RAISE Study show that early care for psychosis heals:

  • Coordinated Specialty Care reduced schizophrenia symptoms 1.5x faster than standard community care
  • Coordinated Specialty Care improved quality of life 2x faster than community care
  • Coordinated Specialty Care accelerated involvement in work and school

How you can help:

We are actively raising funds to help launch and fund the early-stage activities of the ASPIRe initiative. As we have done so successfully in the past with other programs and initiatives, we will leverage $5 million in funding from state and local governments. Your support will fill crucial gaps that will help get ASPIRe off the ground!

Youth deserve the opportunity to grow mentally healthy and emotionally strong. One Mind’s ASPIRe initiative will offer youth rising hope to avoid SPI’s setbacks and grow into the resilient citizens that will lift our society to a brighter future.

Please make a donation to One Mind to help those who have a Serious Psychiatric Illness.

We’re off to a great start in supporting this important program! 

The ASPIRe initiative was the designated recipient of the ‘Fund-a-Need’ event during the VIP Dinner at the 2018 Music Festival for Brain Health. Guests in attendance pledged over $710,000 to support this important program!

Funded Programs:

Learning Health Care Network: 

The California Learning Healthcare Network will merge data from programs around California for combined analysis, so each program can share its strengths and address its weaknesses. As ideas and techniques propagate, all programs will learn to provide the best outcomes for the youth they serve. The California network plans to merge with other regional networks to form a national platform from which to implement and improve evidence based care for all youth with early SPI.


One Mind has partnered with the NIMH to sponsor the North American Prodrome Longitudinal Study (NAPLS), a nine-university consortium investigating how to detect and treat psychosis before it fully develops, in the prodrome stage, when the best chance of recovery still exists. Building on the discoveries the NAPLS has made in its 14-year history, ASPIRe will assist NAPLS scientists to develop easy-to-use prodrome diagnostics. This advance will enable the adoption of the prodrome phase into the official manual for psychiatric diagnosis, thus enabling insurance companies to finally cover prodrome treatment, empowering recovery for thousands of youth annually.

Strong 365: 

Strong365 is a One Mind program that connects youth to care for early psychosis by reaching them where they are: online. Combining search-engine ads with online screening, peer chat and educational media, the Strong365 campaign partners with Northwell Health in New York to develop and apply innovative techniques to help more youth with early SPI access lifesaving care early, when it matters most. With funding from ASPIRe, Strong365 will expand into more areas and pioneer even more ways to ensure that youth with early SPI can reach their fullest potential.

Expanding Coordinated Specialty Care Clinics:

To enhance access to gold-standard care for youth with early SPI and to pilot treatment innovations, One Mind is partnering with local philanthropists and funding organizations to expand our targeted Coordinated Specialty Care efforts. One current partner we are doing this with is the Elizabeth Morgan Brown Memorial Fund, focusing on the development of a CSC program in Sonoma County, CA. If you would like to financially support this effort, please select their name on the second page of our online donation interface.

To learn about the Sonoma County Youth Psychosis Treatment Program grant, please visit this page of our website.

Elizabeth Morgan Brown One Mind