Identifying and funding critical and groundbreaking brain health research

Given the challenges of understanding and finding therapies for brain illnesses and injuries, the One Mind Rising Star Awards encourage the community of researchers to innovate in their basic and translational science to benefit patients, while supporting the research of emerging leaders in the field.
In 2017, One Mind Institute, in collaboration with Janssen Research and Development, granted two major awards for research related to psychiatric illness. Chosen by One Mind’s Scientific Advisory Board, each Rising Star recipient will receive up to $250,000 to fund research for their studies.

About the Awards

One Mind / Janssen Rising Star Translational Research Award in Honor of the late Jeffrey S. Nye, M.D., Ph.D.

This award focuses on research toward novel therapies for psychiatric illness with the objective to advance the translation of scientific knowledge of underlying disease mechanisms in bipolar disorder, schizophrenia, and major depression toward benefits to patients and the healthcare system. Specifically, the program will support translational research on innovative targets, with the potential to advance discovery of therapeutic approaches in the near term. The emphasis will be on the approaches that provide a viable path toward renormalizing or compensating for novel biological alterations or those that have already been discovered. This award is not specifically focused to advance the understanding of the fundamental mechanisms of psychiatric diseases.

The One Mind Rising Star Early Diagnostics Basic Research Award

This award focuses on research emphasizing innovative strategies and technologies toward the discovery and/or validation of biomarkers to predict risk for, or diagnose the onset of, severe behavioral illness, either neuropsychiatric or substance-use-based. These biomarkers may arise from processes that are either endogenous, microbiomic, related to the biological consequences of trauma (physical or emotional), or newly discovered.

The 2017 Rising Star Awardees

One Mind Institute’s Scientific Advisory Board has chosen Alik S. Widge, M.D., Ph.D., to receive the 2017 One Mind / Janssen Rising Star Translational Research Award in Honor of the late Jeffrey S. Nye, M.D., Ph.D., and Ian Maze, Ph.D., to receive the 2017 One Mind Rising Star Early Diagnostics Basic Research Award.

Dr. Widge is Assistant Professor of Psychiatry at Massachusetts General Hospital and Harvard Medical School. Toward boosting the recovery of patients with illnesses such as schizophrenia, major depression, or obsessive-compulsive disorder, Dr. Widge proposes to identify precisely the brain circuits that govern the inflexibility of thinking common among patients with such illnesses, and to test whether neurostimulation of these circuits could improve mental flexibility.

Watch Dr. Widge’s Scientific Symposium presentation at the 2017 Music Festival for Brain Health.

Dr. Maze is Assistant Professor of Neuroscience and Pharmacological Sciences at the Icahn School of Medicine at Mount Sinai. Building on his recent discoveries in depression research, Dr. Maze proposes a potent aim: to determine whether testing the blood for reduced levels of a serotonin-modified protein could help to predict susceptibility to depression under stress, to diagnose major depressive disorder, and/or to predict whether antidepressant medications might help specific patients.

Watch Dr. Maze’s Scientific Symposium presentation at the 2017 Music Festival for Brain Health.

Read about past Rising Star Awardees and other One Mind funded researchers on our Research Updates page.

For more information on the Rising Star Awards, please contact us.